The Ras switch in structural and historical perspective
Simulating Ras: 30 years of progress - NCI
RAS(ON) Inhibitors | Revolution Medicines
Pharmaceuticals | Free Full-Text | A Rational Design of α-Helix-Shaped Peptides Employing the Hydrogen-Bond Surrogate Approach: A Modulation Strategy for Ras-RasGRF1 Interaction in Neuropsychiatric Disorders
Mapping the functional versatility and fragility of Ras GTPase signaling circuits through in vitro network reconstitution | eLife
Cancers | Free Full-Text | Cutting the Brakes on Ras—Cytoplasmic GAPs as Targets of Inactivation in Cancer
Binding of active Ras and its mutants to the Ras binding domain of PI-3-kinase: A quantitative approach to KD measurements - ScienceDirect
Mapping the functional versatility and fragility of Ras GTPase signaling circuits through in vitro network reconstitution | eLife
Pharmaceuticals | Free Full-Text | A Rational Design of α-Helix-Shaped Peptides Employing the Hydrogen-Bond Surrogate Approach: A Modulation Strategy for Ras-RasGRF1 Interaction in Neuropsychiatric Disorders
Simulating Ras: 30 years of progress - NCI
Phosphorylation promotes binding affinity of Rap-Raf complex by allosteric modulation of switch loop dynamics | Scientific Reports
JPM | Free Full-Text | Targeting KRAS in Pancreatic Cancer
Approach for targeting Ras with small molecules that activate SOS-mediated nucleotide exchange | PNAS
Raf promotes dimerization of the Ras G-domain with increased allosteric connections | PNAS
Raf promotes dimerization of the Ras G-domain with increased allosteric connections | PNAS
Potential for Next Generation RAS Inhibitors in Adult and Pediatric Cancers
Frontiers | The Multi-Level Mechanism of Action of a Pan-Ras Inhibitor Explains its Antiproliferative Activity on Cetuximab-Resistant Cancer Cells
Simulating Ras: 30 years of progress - NCI
RCSB PDB - 1U8Y: CRystal structures of Ral-GppNHp and Ral-GDP reveal two novel binding sites that are also present in Ras and Rap
Molecular recognition of RAS/RAF complex at the membrane: Role of RAF cysteine-rich domain | Scientific Reports
Raf promotes dimerization of the Ras G-domain with increased allosteric connections | PNAS
Modeling the Role of G12V and G13V Ras Mutations in the Ras-GAP-Catalyzed Hydrolysis Reaction of Guanosine Triphosphate | Biochemistry
Structural Insights into the BRAF Monomer-to-dimer Transition Mediated by RAS Binding | bioRxiv
The Activation of RalGDS Can Be Achieved Independently of Its Ras Binding Domain: IMPLICATIONS OF AN ACTIVATION MECHANISM IN Ras EFFECTOR SPECIFICITY AND SIGNAL DISTRIBUTION - ScienceDirect
Raf promotes dimerization of the Ras G-domain with increased allosteric connections | PNAS
BRET-based RAS biosensors that show a novel small molecule is an inhibitor of RAS-effector protein-protein interactions | eLife
Biomolecules | Free Full-Text | Hyperactivated RAGE in Comorbidities as a Risk Factor for Severe COVID-19—The Role of RAGE-RAS Crosstalk
